Date of Birth    January 18, 1953

• 1976 Joined the Company
• 1995 Deputy President of Chugai Pharma Europe Ltd. (U.K.)
• 2000 Head of Business Strategy Planning Office
• 2002 Vice President, Head of Corporate Planning Dept.
• 2004 Senior Vice President, Head of Corporate Planning Dept.
• 2005 Senior Vice President, Deputy Managing Director of Sales & Marketing Group
  Senior Vice President, Head of Strategic Marketing Unit
• 2008 Senior Vice President, Head of Lifecycle Management & Marketing Unit
• 2010 Director, Executive Vice President
• 2012 Representative Director, President & COO
• 2016 Outside Director of Asahi Group Holdings, Ltd.
• 2018 Representative Director, President & CEO
• 2020 Representative Director, Chairman & CEO
• 2021 Representative Director, Chairman (to present)

Date of Birth    August 11, 1957

• 1984 Joined the Company
• 1991 General Manager of London Representative Office
• 1993 Director
• 1994 Director, Head of Medical Information Div.
• 1995 Director, Head of Clinical Research & Development Division
• 1996 Director, Deputy Head of Research & Development Division
• 1997 Director, Senior Vice President
• 1998 Senior Vice President
• 2000 Director, Senior Vice President
• 2002 Director, Deputy President
• 2003 Director, Deputy President, Vice President
• 2004 Representative Director, Deputy President
• 2006 Representative Director, President of Chugai Pharma Manufacturing Co., Ltd.
• 2012 Representative Director, Deputy Chairman (to present)

Date of Birth    April 5, 1963

• 1987 Joined the Company
• 2008 Department Manager of Lifecycle Management Dept. II
• 2009 Department Manager and Lifecycle Leader of Lifecycle Management Dept. II
• 2011 President of Roche Products (Ireland) Limited
• 2013 Head of Oncology Unit, Marketing & Sales Div. of the Company
• 2014 Executive Officer, Head of Oncology Unit,
  Marketing & Sales Div. of the Company
• 2015 Executive Officer, Head of Corporate Planning Dept. of the Company
• 2017 Executive Vice President, Head of Corporate Planning Dept. of the Company
• 2018 Executive Vice President, Co-Head of Project & Lifecycle Management Unit
• 2020 Representative Director, President & COO
• 2021 Representative Director, President & CEO (to present)

Date of Birth    December 2, 1944

• 1968 Joined The Sumitomo Bank, Ltd. (“SB”)
• 1994 Director of SB
• 1998 Managing Director of SB
• 1999 Managing Director and Managing Executive Officer of SB
• 2001 Senior Managing Director and Senior Managing Executive Officer of SB
  Senior Managing Director and Senior Managing Executive Officer of Sumitomo Mitsui Banking Corporation (“SMBC”)
• 2002 Senior Managing Director of Sumitomo Mitsui Financial Group, Inc. (“SMFG”)
• 2003 Deputy President and Executive Officer of SMBC
• 2005 Chairman of SMFG
  President and Chief Executive Officer of SMBC
• 2008 Outside Director of Panasonic Corporation
  Outside Director of Nankai Electric Railway Co., Ltd.
• 2009 Director of Nikko Cordial Securities Inc.
• 2014 Outside Director of Kao Corporation.
  Outside Director of Komatsu Ltd.
• 2015 Director of the Company (to present)
  Non-Executive Director of The Bank of East Asia (to present)
• 2017 Director of SMFG
  Honorary Advisor of SMFG (to present)
• 2019 Outside Director of Rengo Co., Ltd. (to present)
  Outside Director of The Royal Hotel, Ltd. (to present)
• 2021 Outside Director of TV TOKYO Holdings Corporation (to present)

Date of Birth    October 10, 1948

• 1971 Joined Toyota Motor Sales Co., Ltd.
• 2001 Member of the Board of Directors of Toyota Motor Corporation (“TMC”)
• 2003 Managing Executive Officer of TMC
• 2005 Senior Managing Director of TMC
• 2009 Representative Director, Executive Vice President of TMC
  Corporate Auditor of Aioi Insurance Co., Ltd.
• 2010 Corporate Auditor of Aioi Nissay Dowa Insurance Co., Ltd.
• 2011 Senior Corporate Auditor of TMC
• 2015 Executive Advisor of TMC
  Representative Director, Chairman of Aioi Nissay Dowa Insurance Co., Ltd.
• 2017 Director of the Company (to present)
  Senior Advisor of Aioi Nissay Dowa Insurance Co., Ltd.
• 2019 Outside Director of Seino Holdings Co., Ltd. (to present)

Date of Birth    February 24, 1948

• 1994 Head of Department of Pediatrics, Jichi Medical University
• 2006 Director of Jichi Children’s Medical Center Tochigi
• 2010 Dean of School of Medicine, Jichi Medical University
• 2012 Visiting Professor of School of Medicine, Shinshu University (to present)
• 2013 Professor Emeritus of Jichi Medical University (to present)
  Vice President of International University of Health and Welfare
• 2014 Director of Japanese Medical Specialty Board (part-time)
• 2015 Vice President of International University of Health and Welfare and Head of IUHW Hospital
• 2017 Chief Medical Officer of Ryoumou Seishi Ryogoen, Kiryu Ryoiku Futabakai Social Welfare Corporation
• 2018 Regent of Tokyo Medical University (part-time) (to present)
• 2020 Director of the Company (to present)

Date of Birth    May 2, 1960

• 1990 Joined Deutsche Lufthansa AG
• 1994 Member of the Executive Board and CEO of Passenger Transport Division of Deutsche Bahn AG
• 2004 CEO of Swiss International Air Lines AG
• 2009 Deputy Chairman of the Executive Board of Deutsche Lufthansa AG
• 2011 Chairman of the Executive Board and CEO of Deutsche Lufthansa AG
• 2014 Chairman of the Board of Directors of Roche Holding Ltd. (to present)
• 2017 Director of the Company (to present)

Date of Birth    August 23, 1966

• 1997 Joined Biogen Idec
• 1999 Managing Director, United Kingdom and Ireland of Biogen Idec
• 2001 Vice President of Finance, Business Planning of Biogen Idec
• 2004 Vice President and General Manager of Neurology Business Unit of Biogen Idec
• 2006 Senior Vice President of Immunology & Ophthalmology Business Unit of Genentech
• 2010 Senior Vice President of BioOncology Business Unit of Genentech
• 2013 Head of Global Product Strategy, Chief Marketing Officer of Roche
• 2017 CEO of Genentech
• 2019 CEO of Roche Pharmaceuticals and Member of the Roche Corporate Executive Committee (to present)
  Director of the Company (to present)

Date of Birth    December 19, 1958

• 1997 Co-founder, President and CEO of Cytokinetics
• 2008 President and CEO of Arete Therapeutics
• 2010 Global Head and Vice President of Genentech Partnering
• 2013 Global Head and Senior Vice President of Genentech Partnering
• 2018 Global Head of Roche Pharma Partnering and Member of the Roche Enlarged Corporate Executive Committee (to present)
• 2019 Director of the Company (to present)

Date of Birth    February 10, 1959

• 1981 Joined the Company
• 2009 Head of Risk Management & Compliance Dept.
• 2011 Head of Corporate Social Responsibility Dept.
• 2015 Head of Corporate Social Responsibility Dept. and General Affairs Dept.
  Head of Corporate Social Responsibility Dept.
• 2016 Associate Vice President, Head of Corporate Social Responsibility Dept.
• 2019 Associate Vice President
  Audit & Supervisory Board Member (to present)

Date of Birth    January 8, 1960

• 1988 Joined the Company
• 2004 Department Manager, Quality & Regulatory Compliance Dept.
• 2009 Department Manager, Drug Safety Coordination Dept.
• 2011 Global PV Head, Pharmacovigilance Manager
• 2013 Head of Drug Safety Div. and Department Manager of Drug Safety Coordination Dept.
• 2015 Vice President, Head of Drug Safety Div.
  Vice President, Head of Quality & Regulatory Compliance Unit, and Head of Drug Safety Div.
• 2018 Senior Vice President, Head of Quality & Regulatory Compliance Unit and Head of Drug Safety Div.
• 2021 Senior Vice President
  Audit & Supervisory Board Member (to present)

Date of Birth    October 25, 1949

• 1974 Joined Arthur Young & Co., Tokyo Office
• 1980 Seconded to Asahi & Co., Osaka Office
• 1983 Seconded to Arthur Young & Co., Los Angeles Office
• 1989 Partner, Asahi Shinwa & Co.
• 1993 Joined Showa Ota & Co.
• 1997 Senior Partner, Showa Ota & Co.
• 2008 Executive Board Member, Ernst & Young ShinNihon LLC
• 2010 Established Nimura Certified Public Accountant Office
• 2012 Outside Director, Sony Corporation
• 2016 Outside Audit & Supervisory Board Member of the Company (to present)

Date of Birth    July 26, 1960

• 1984 Joined Bridgestone Corporation
• 1998 CFO of BTR Power Systems Japan
• 2001 Vice President of Tokyo University of Agriculture and Technology TLO Co., Ltd.
• 2003 Director, Technology Transfer Center of Tokyo Medical and Dental University
• 2009 Project Coordinator of Innovation Initiative Network Japan
  Visiting Professor of Tokyo Medical and Dental University
• 2011 Specially Appointed Professor of Kyoto Prefectural University of Medicine
• 2013 Executive Officer of Bridgestone Corporation
• 2014 Auditor (part-time) of Japan Agency for Marine-Earth Science and Technology (to present)
• 2017 Director of CellBank Corp. (to present)
• 2019 Outside Audit & Supervisory Board Member of the Company (to present)
• 2020 External Director, Kosé Corporation (to present)
  Executive Vice President, Kyushu University (part-time)

Date of Birth    January 11, 1963

• 1988 Registered as an attorney-at-law (Daini Tokyo Bar Association)
  Joined Anderson Mōri & Tomotsune
• 1993 Registered as an attorney-at-law in the state of New York
• 1997 Partner of Anderson Mōri & Tomotsune (to present)
• 2007 Outside Corporate Auditor of LIFENET INSURANCE COMPANY (to present)
• 2010 Part-time Lecturer at School of Law, The University of Tokyo
• 2011 Outside Corporate Auditor of Bridgestone Corporation
• 2016 Outside Director of Bridgestone Corporation (to present)
•   Outside Audit & Supervisory Board Member of Mercuria Investment Co., Ltd. (to present)
• 2019 Visiting Professor of School of Law, The University of Tokyo (to present)
• 2020 Outside Audit & Supervisory Board Member of the Company (to present)