Directors & Officers

Representative Directors
Directors
Audit & Supervisory Board Members
Executive Officers

As of July 27, 2017

Representative Directors

	Osamu Nagayama Chairman & CEO Career Summary 1978 Joined the Company 1985 Deputy General Manager of Development and Planning Div. and Director 1987 Director & Senior Vice President 1989 Representative Director & Deputy President 1992 Representative Director, President & CEO 2010 Outside Director, Sony Corporation (to present) 2012 Representative Director, Chairman & CEO (to present)
	Motoo Ueno Deputy Chairman, Corporate Social Responsibility, Audit Career Summary 1984 Joined the Company 1991 General Manager of London Representative Office 1993 Director 1994 Director and General Manager of Medical Information Div. 1995 Director and General Manager of Clinical Research & Development Division 1996 Director and Deputy General Manager of Research and Development Division 1997 Director & Senior Vice President 1998 Senior Vice President 2000 Director & Senior Vice President 2002 Director & Deputy President 2003 Director & Deputy President, Vice President 2004 Representative Director & Deputy President 2006 Representative Director & President, Chugai Pharma Manufacturing Co., Ltd. 2012 Representative Director & Deputy Chairman (to present)
	Tatsuro Kosaka President & COO Career Summary 1976 Joined the Company 1995 Deputy President of Chugai Pharma Europe Ltd. (U.K.) 2000 General Manager of Business Strategy Planning Office 2002 Vice President & General Manager of Corporate Planning Dept. 2004 Senior Vice President & General Manager of Corporate Planning Dept. 2005 Senior Vice President & Deputy Managing Director of Sales & Marketing Group, Senior Vice President & Head of Strategic Marketing Unit 2008 Senior Vice President & Head of Lifecycle Management & Marketing Unit 2010 Director & Executive Vice President, Head of Lifecycle Management & Marketing Unit 2011 Director & Executive Vice President 2012 Representative Director, President & COO (to present)

Directors

	Yoshio Itaya Executive Vice President, CFO, General Manager of Finance Supervisory Div., In charge of IT Supervisory Div. Career Summary 2003 Joined the Company, Senior Specialist of Finance & Accounting Div. 2006 Vice President and General Manager of Finance & Accounting Div. 2007 Vice President and General Manager of Corporate Planning Dept. 2010 Senior Vice President and General Manager of Finance Supervisory Div. and Finance & Accounting Dept. 2011 Senior Vice President, CFO, General Manager of Finance Supervisory Div. (to present) and Finance & Accounting Dept. 2012 Director, Executive Vice President & CFO (to present)
	Christoph Franz Chairman of the Board of Directors of Roche Holding Ltd. Member of the Board of Directors of Stadler Rail (Switzerland) Member of the Board of Directors of Zurich Insurance Group Ltd (Switzerland) Career Summary 1990 Joined Deutsche Lufthansa AG 1994 Member of the Executive Board and CEO of Passenger Transport Division of Deutsche Bahn AG 2004 CEO of Swiss International Air Lines AG 2009 Deputy Chairman of the Executive Board of Deutsche Lufthansa AG 2011 Chairman of the Executive Board and CEO of Deutsche Lufthansa AG 2014 Chairman of the Board of Directors of Roche Holding Ltd. (to present) 2017 Director of the Company (to present)
	Daniel O’Day Chief Executive Officer of Roche Pharmaceuticals, Member of the Roche Corporate Executive Committee, Member of the Genentech Board of Directors Career Summary 1987 Joined Roche Pharma USA 1995 Director Human Resources, Roche Pharma U.S.A. 1996 Director Product Marketing, Roche Pharma U.S.A. 1998 Business Unit Head, Arthritis and Respiratory, Roche Pharma Headquarters 1999 Lifecycle Leader Tamiflu, Roche Pharma Headquarters 2001 Head Corporate Planning, Roche Pharma Japan 2003 General Manager, Roche Pharma Denmark 2006 President & CEO of Roche Molecular Diagnostics 2010 COO Roche Diagnostics Division, Member of the Corporate Executive Committee 2012 COO Roche Pharmaceuticals Division, Member of the Roche Corporate Executive Committee, Member of the Genentech Board of Directors 2013 Director of the Company (to present) 2016 CEO Roche Pharmaceuticals, Member of the Roche Corporate Executive Committee, Member of the Genentech Board of Directors (to present)
	Sophie Kornowski-Bonnet Head of Roche Partnering and Member of the Roche Enlarged Corporate Executive Committee Career Summary 1985 Abbott Diagnostic Division – Paris – France, Scientific Manager 1989 Abbott Pharmaceutical Products – Chicago, U.S.A., Marketing Research Analyst 1990 Abbott Pharmaceutical Products – New York, U.S.A., Neuroscience Sales Representative 1991 Sanofi Winthrop – New York, U.S.A., Director, Strategic Marketing, Diagnostic Imaging 1994 Sanofi Winthrop – Paris, France, Director, Neuroscience Business Unit 1996 Merck Sharp & Dohme Paris, France, Director, Marketing Research and Strategic Planning 1997 Merck Sharp & Dohme Israel, Managing Director 2000 Vice-President Arthritis and Analgesia Franchise, Merck & Co. Inc. U.S.A. 2002 Merck Sharp & Dohme Paris, France, Director, Rheumatology Division 2006 Merck Sharp & Dohme Paris, France, Director, Cardiovascular Division 2007 Roche Pharma, France, General Manager 2012 Head of Roche Partnering, Member of the Roche Enlarged Corporate Executive Committee (to present) Director of the Company (to present)

< Outside Directors >

	Yasuo Ikeda* Vice-Chairman of the Board of Directors, Musashi Academy of the Nezu Foundation, University Professor of Waseda University, Professor Emeritus of Keio University Career Summary 1979 Director of Keio University Hospital Blood Center 1991 Professor of Internal Medicine of Keio University School of Medicine 2001 Director of Keio University Center for Integrated Medical Research 2005 Dean of Keio University School of Medicine 2009 Professor Emeritus of Keio University (to present) Professor of Department of Life Science and Medical Bioscience of Graduate School of Advanced Science and Engineering of Faculty of Science and Engineering of Waseda University 2010 Outside Director of the Company (to present) 2013 Vice-Chairman of the Board of Directors, Musashi Academy of the Nezu Foundation (to present) 2014 Specially Appointed Professor of Waseda University (to present)
	Masayuki Oku* Honorary Advisor of Sumitomo Mitsui Financial Group, Inc. Career Summary 1968 Joined The Sumitomo Bank, Ltd. (SB) 1994 Director, SB 1998 Managing Director, SB 1999 Managing Director and Managing Executive Officer, SB 2001 Senior Managing Director and Senior Managing Executive Officer, SB, Senior Managing Director and Senior Managing Executive Officer of Sumitomo Mitsui Banking Corporation (SMBC) 2002 Senior Managing Director of Sumitomo Mitsui Financial Group, Inc. (SMFG) 2003 Deputy President, SMBC 2005 Chairman, SMFG, President and Chief Executive Officer, SMBC 2015 Outside Director of the Company (to present) 2017 Honorary Advisor, SMFG (to present)
	Yoichiro Ichimaru* Executive Advisor of TOYOTA MOTOR CORPORATION Senior Advisor of Aioi Nissay Dowa Insurance Co., Ltd. Career Summary 1971 Joined Toyota Motor Sales Co., Ltd. 2001 Member of the Board of Directors of TOYOTA MOTOR CORPORATION (“TMC”) 2003 Managing Executive Officer of TMC 2005 Senior Managing Director of TMC 2009 Representative Director, Executive Vice President of TMC Corporate Auditor of Aioi Insurance Co., Ltd. 2010 Corporate Auditor of Aioi Nissay Dowa Insurance Co., Ltd. 2011 Senior Corporate Auditor of TMC 2015 Executive Advisor of TMC (to present) Representative Director, Chairman of Aioi Nissay Dowa Insurance Co., Ltd. 2017 Outside Director of the Company (to present) Senior Advisor of Aioi Nissay Dowa Insurance Co., Ltd. (to present)

*	Yasuo Ikeda, Masayuki Oku and Yoichiro Ichimaru are independent directors pursuant to the regulations of Tokyo Stock Exchange, Inc.

Audit & Supervisory Board Members

Shunji Yokoyama
Audit & Supervisory Board Member (full-time)

Career Summary

1981 Joined the Company
2002 General Manager of Clinical Research Dept. 1
2004 Vice President, General Manager of Clinical Research & Development Div.
2007 Vice President, Deputy General Manager of Corporate Regulatory Compliance & Quality Assurance Div. and Head of Drug Safety Unit
2009 Vice President, General Manager of Drug Safety Div.
2011 Vice President, Head of Quality & Regulatory Compliance Unit and General Manager of Drug Safety Div.
2013 Senior Vice President, Head of Regulatory & Quality Management Unit
2015 Audit & Supervisory Board Member (full-time) (to present)

Mamoru Togashi
Audit & Supervisory Board Member (full-time)

Career Summary

1982 Joined the Company
2004 President of Chugai Business Support Co., Ltd.
2006 General Manager of Corporate Communications Dept.
2009 General Manager of Human Resources Management Dept.
2010 Vice President, General Manager of Human Resources Supervisory Div., Human Resources Management Dept.
2016 Vice President, General Manager of Human Resources Supervisory Div.
2017 Audit & Supervisory Board Member (full-time) (to present)

< Audit & Supervisory Board Members (Outside)>

Hisashi Hara
General Representative of the Asia-Pacific region, The Law Office of Nagashima Ohno & Tsunematsu

Career Summary

1975 Registered as an attorney-at-law (Dai-ichi Tokyo Bar Association)
1975 Joined Nagashima & Ohno (currently, Nagashima, Ohno & Tsunematsu)
1983 Partner of Nagashima & Ohno
1991 Managing Partner of Nagashima & Ohno
2006 Chairman of Nagashima, Ohno & Tsunematsu
2006 Administrative Council Member of the University of Tokyo
2008 Outside Corporate Auditor, JPMorgan Securities Japan Co., Ltd.
2012 Outside Audit & Supervisory Board Member of the Company (to present)
2013 General Representative of the Asia-Pacific region, The Law Office of Nagashima Ohno & Tsunematsu (to present)

Takaaki Nimura*
Representative of Nimura Certified Public Accountant Office, Outside Director and Chairman of Audit Committee of Sony Corporation

Career Summary

1974 Joined Arthur Young & Co., Tokyo Office
1980 Seconded to Asahi & Co., Osaka Office
1983 Seconded to Arthur Young & Co., Los Angeles Office
1989 Partner of Asahi Shinwa & Co.
1993 Joined Showa Ota & Co.
1997 Senior partner of Showa Ota & Co.
2008 Executive Board Member of Ernst & Young ShinNihon LLC
2010 Established Nimura Certified Public Accountant Office
2012 Director of Sony Corporation (to present)
2016 Outside Audit & Supervisory Board Member of the Company (to present)

*	Takaaki Nimura is an independent Audit & Supervisory Board Member pursuant to the regulations of Tokyo Stock Exchange, Inc.

Executive Officers

Yoshio Itaya
Executive Vice President, CFO, General Manager of Finance Supervisory Div.,
In charge of IT Supervisory Div.

Shinya Unno
Senior Vice President, General Manager of Human Resources Supervisory Div., General Affairs, Secretarial

Yasushi Ito
Senior Vice President, Head of Project & Lifecycle Management Unit, In charge of Regulatory & Quality Management, Clinical Development, Drug Safety, Medical Affairs

Hisafumi Okabe
Senior Vice President, In charge of Research, Translational Clinical Research

Susumu Kato
Senior Vice President, General Manager of Marketing & Sales Div.

Hitoshi Kuboniwa
Senior Vice President, In charge of Pharmaceutical Technology

Keiji Kono
Senior Vice President, External Affairs, Global Health Policy

Osamu Okuda
Senior Vice President, General Manager of Corporate Planning Dept.

Junichi Ebihara
Senior Vice President, General Manager of Legal Dept.

Tetsuya Yamaguchi
Vice President, Department Manager of Business Development Dept.

Yoshiaki Ohashi
Vice President, Head of Quality & Regulatory Compliance Unit and General Manager of Drug Safety Div.

Toshihiko Komori
Vice President, General Manager of Translational Clinical Research Div.

Hisanori Takanashi
Vice President, General Manager of Clinical Development Div.

Shinji Hidaka
Vice President, Deputy General Manager of Marketing & Sales Div. (Marketing & Sales Promotion)

Kouichi Nishikawa
Vice President, Deputy General Manager of Marketing & Sales Div. (Overseas Business)

Tadahiko Sato
Vice President, Head of Kanto-Minami Regional Management Office

Toshiaki Itagaki
Vice President, General Manager of IT Supervisory Div. and General Manager of Finance & Accounting Dept.