Share Ownership

Major Shareholders

Top 10 Largest Shareholders*

As of December 31, 2018

Shareholder Shares Held
(thousands of shares)
Shareholding Percentage
(%)
Voting Interest
(%)
Roche Holding Ltd 335,223 61.25 61.27
The Master Trust Bank of Japan, Ltd. (Trust Account) 29,342 5.36 5.36
Japan Trustee Services Bank, Ltd. (Trust Account) 16,320 2.98 2.98
STATE STREET BANK AND TRUST COMPANY 505001 15,614 2.85 2.85
JP MORGAN CHASE BANK 380055 13,924 2.54 2.54
STATE STREET BANK WEST CLIENT - TREATY 505234 4,231 0.77 0.77
Japan Trustee Services Bank, Ltd. (Trust Account 5) 4,091 0.74 0.74
Trust & Custody Services Bank, Ltd. (Securities Investment Trust Account) 3,829 0.69 0.70
Japan Trustee Services Bank, Ltd. (Trust Account 7) 3,748 0.68 0.68
SSBTC CLIENT OMNIBUS ACCOUNT 3,651 0.66 0.66

*The Company is excluded from the ten major shareholders listed in the table above, although the Company holds 12,459,413 shares of treasury stock.

Ownership Profile

Ownership Profile
Ownership Profile Shares
(thousands of shares)
Shares Issued
(%)
Shareholders
Roche Holding Ltd 335,223 59.89 1
Foreign Corporations except Roche 101,646 18.16 751
Financial Institutions (Trust Banks, Insurance Companies) 79,685 14.23 64
Individuals and Other 19,865 3.54 18,941
Financial Instruments Firm (Securities Firms) 5,751 1.02 39
Other Corporations 5,054 0.90 150
Treasury stock 12,459 2.22 1

Number of Shareholders

Number of Shareholders

Purchase of Treasury Stock

Acquisition Period Shares Acquired
(thousands of shares)
Total Acquisition Cost (Yen) Average Cost per Share (Yen)
2007 Feb. 8 - Mar. 20 9,500 27,583,568,000 2,904
2004 Oct. 10 - Nov. 16 1,000 1,642,702,200 1,643
2003 Aug. 28 - Sep. 5 800 1,024,559,600 1,281
Jul. 28 2,000 2,780,000,000 1,390
Jun. 26 1,500 2,044,500,000 1,363
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Shareholder Information

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