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Share Ownership

Major Shareholders

Top 10 Largest Shareholders*

As of December 31, 2016

Shareholder Shareholding Percentage
(%)
Voting Interest
(%)
Roche Holding Ltd 335,223 61.36 61.38
The Master Trust Bank of Japan, Ltd. (Trust account) 22,271 4.07 4.07
Japan Trustee Services Bank, Ltd. (Trust account) 18,540 3.39 3.39
JP MORGAN CHASE BANK 385147 14,288 2.61 2.61
JP MORGAN CHASE BANK 380055 4,920 0.90 0.90
JP MORGAN CHASE BANK 385632 4,476 0.81 0.81
Trust & Custody Services Bank, Ltd. (Trust Collateral Account) 4,045 0.74 0.74
STATE STREET BANK WEST CLIENT - TREATY 505234 3,761 0.68 0.68
Chugai Pharmaceutical Employee Shareholders' Association 3,158 0.57 0.57
Sumitomo Life Insurance Company 3,000 0.54 0.54

*The Company is excluded from the ten major shareholders listed in the table above, although the Company holds 13,417,953 shares of treasury stock.
Shareholding percentage was calculated based on the total number of the issued shares excluding the number of treasury stock.

Ownership Profile

Ownership Profile

Ownership Profile Shares Issued
(%)
Shareholders
Roche Holding Ltd 335,223 59.89 1
Foreign Corporations except Roche 93,192 16.65 575
Financial Institutions (Trust Banks, Insurance Companies) 77,166 13.78 79
Individuals and Other 24,224 4.32 26,175
Financial Instruments Firm (Securities Firms) 11,068 1.97 56
Other Corporations 5,391 0.96 192
Treasury stock 13,417 2.39 1

Number of Shareholders

Number of Shareholders

Purchase of Treasury Stock

Acquisition Period Shares Acquired
(thousands of shares)
Total Acquisition Cost (Yen) Average Cost per Share (Yen)
2007 Feb. 8 - Mar. 20 9,500 27,583,568,000 2,904
2004 Oct. 10 - Nov. 16 1,000 1,642,702,200 1,643
2003 Aug. 28 - Sep. 5 800 1,024,559,600 1,281
Jul. 28 2,000 2,780,000,000 1,390
Jun. 26 1,500 2,044,500,000 1,363