Chugai is promoting R&D based on organic collaboration between the respective functions of its two core research laboratories in Japan: Chugai Life Science Park Yokohama (Yokohama City, Kanagawa Prefecture) and Ukima (Kita-ku, Tokyo).
Moreover, Chugai is utilizing the Roche Group’s network to expand its drug research structure globally in a variety of fields, making it possible to discover promising new drug candidates early and to shorten development time.
- Chugai Life Science Park Yokohama
- As a base for drug discovery research, we conduct various drug development activities, from research on target molecules, to the creation and optimization of lead materials (the starting point for drug candidates), preclinical development research, and drug development research.
- Ukima Research Laboratories
- As a base for late-stage development research, we conduct pharmaceutical API manufacturing process research, product design (formulation and packaging) and production method research, facility design and production technology research, analysis of the structure and physical properties of pharmaceuticals, and quality testing methods.
Chugai has set up satellite labs to shorten drug discovery and development time and to continuously create innovative R&D projects.
Chugai Pharmabody Research Pte. Ltd. (Singapore)
Chugai Pharmabody Research utilizes Chugai’s proprietary antibody engineering technologies to quickly and efficiently generate innovative therapeutic antibody candidates that provide unprecedented value.
Collaboration Laboratory sited at IFReC
A comprehensive collaboration for advanced research in immunology between the Osaka University Immunology Frontier Research Center (IFReC) and Chugai was made in May 2016. Based on the collaboration, Joint Research Chair of Innovative Drug Discovery in Immunology has been set up at IFReC. Exploratory research for drug discovery is being conducted through synergy between IFReC’s latest research results and Chugai’s proprietary antibody engineering technologies.
Collaboration Laboratory sited at National Cancer Center Research Institute
Search for new CIT targets through immune cell profiling of cancer microenvironment
National Cancer Center Research Institute website:
Collaboration Laboratory sited at the University of Tokyo Center of Innovation (COI)
Search for new targets in rheumatic diseases through GWAS/eQTL Analysis
The University of Tokyo COI website:
- Genome wide association study (GWAS): Research approach to identify association of genotypes with phenotypes of diseases by testing for differences in the allele frequency of genetic variants
- eQTL: A locus that explains a fraction of the genetic variance of a gene expression phenotype