Chugai Pharmaceutical Co., Ltd. announced today that it has filed a patent infringement lawsuit in the United States District Court for the District of Delaware as follows.

1. Date of Complaint
   November 15, 2018 (local time)
2. Reasons for the Action
   Chugai alleges that the anti-C5 antibody ALXN1210 (ravulizumab) product, an investigational drug developed by Alexion Pharmaceuticals, Inc., infringes one of its U.S. patents (U.S. Patent No. 9,890,377) relating to its proprietary antibody engineering technology. Thus, Chugai filed a patent infringement lawsuit against Alexion requesting a judgment that the ALXN1210 product infringes Chugai’s U.S. patent and injunctive relief precluding manufacturing and selling of the ALXN1210 product within the U.S.
3. Defendant
   
   1. Name:
      Alexion Pharmaceuticals, Inc.
   2. Address:
      121 Seaport Blvd., Boston, Massachusetts, 02210, USA
4. Prospects
   No changes are expected to be made to Chugai’s financial prospects at this point.