CHUGAI PHARMACEUTICAL CO., LTD.

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Share Ownership

Major Shareholders

Top 10 Largest Shareholders*

As of June 30, 2011

Shareholder Shares Issued
(%)
Voting Interest
(%)
Roche Pharmholding B.V. 335,223 59.89 61.62
Japan Trustee Services Bank, Ltd. (Trust account) 11,216 2.00 2.06
The Master Trust Bank of Japan, Ltd. (Trust account) 10,887 1.94 2.00
Deutsche Securities Inc. 5,940 1.06 1.09
JPMorgan Chase Bank 385147 5,321 0.95 0.97
Tokio Marine & Nichido Fire Insurance Co., Ltd. 4,475 0.79 0.82
Mellon Bank, N.A. as Agent for its Client Mellon Omnibus US Pension 4,033 0.72 0.74
Northern Trust Co. (AVFC) Sub A/C American Clients 3,697 0.66 0.67
Chugai Pharmaceutical Employee Shareholders' Association 3,448 0.61 0.63
State Street Bank and Trust Company 505225 3,050 0.54 0.56

*The Company is excluded from the ten major shareholders listed in the table above, although the Company holds 15,492,654 shares of treasury stock.

Ownership Profile

Ownership Profile

Ownership Profile Shares Issued
(%)
Shareholders
Roche Pharmholding B.V. 335,223 59.89 1
Foreign Corporations except Roche 88,308 15.78 447
Financial Institutions (Trust Banks, Insurance Companies) 55,758 9.96 75
Individuals and Other 41,698 7.45 49,296
Treasury stock 15,492 2.77 1
Financial Instruments Firm (Securities Firms) 17,118 3.06 61
Other Corporations 6,086 1.09 279

Number of Shareholders

Number of Shareholders

Purchase of Treasury Stock

Acquisition Period Shares Acquired Total Acquisition Cost (Yen) Average Cost per Share (Yen)
2007 Feb. 8 - Mar. 20 9,500,000 27,583,568,000 2,904
2004 Oct. 10 - Nov. 16 1,000,000 1,642,702,200 1,643
2003 Aug. 28 - Sep. 5 800,000 1,024,559,600 1,281
Jul. 28 2,000,000 2,780,000,000 1,390
Jun. 26 1,500,000 2,044,500,000 1,363