CHUGAI PHARMACEUTICAL CO., LTD.

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Directors & Officers

as of January 01, 2012

Representative Directors

Osamu Nagayama
Motoo Ueno

Directors

Ryuzo Kodama
Dr. Tatsumi Yamazaki
Tatsuro Kosaka

<Outside Directors>

Mitsuo Ohashi *
Adviser, SHOWA DENKO K.K.
Yasuo Ikeda
Professor of the Waseda University, Faculty of Science and Engineering, Department of Life Science and Medical Bioscience
Abraham E. Cohen
Chairman of Chugai Pharma USA.
William M. Burns
Director, Roche
Pascal Soriot
Roche Pharmaceuticals Division, COO
Jean-Jacques Garaud
Head Roche Pharma Research & Early Development (pRED)
Daniel Zabrowski
Head of Pharma Partnering, Roche

* Mitsuo Ohashi is independent director as stipulated under the Tokyo Stock Exchange guideline

Corporate Auditors

Dr. Yasuhiro Tsuji (full-time)
Chugai Research Institute for Medical Science, Inc. / Medical Culture Inc. / Chugai Clinical Research Center Co., Ltd.
Kotaro Miwa (full-time)
Chugai Pharma Manufacturing Co., Ltd. / CBS Co., Ltd. / Chugai Distribution Co., Ltd.

<Outside Corporate Auditors>

Yasunori Fujii *
Special Assigned Professor of Shizuoka Sangyo University
Toshio Kobayashi
Partner, The Law Offices of Nagashima Ohno & Tsunematsu

* Yasunori Fujii is independent director as stipulated under the Tokyo Stock Exchange guideline

Executive Officers

Osamu Nagayama
President CEO / COO
Motoo Ueno
Deputy President  Corporate Social Responsibility, Audit
Ryuzo Kodama
Deputy President  General Manager of IT Supervisory Div.
Dr. Tatsumi Yamazaki
Deputy President
Tatsuro Kosaka
Executive Vice President  Business Development
Naotaka Nakamura
Executive Vice President
Dr. Yutaka Tanaka
Senior Vice President  Head of Lifecycle Management & Marketing Unit, Overseas Development
Dr. Hidetoshi Ushio
Senior Vice President  General Manager of Pharmaceutical Technology Div.
Masaaki Tohaya
Senior Vice President  General Manager of Sales Div.
Shin-ya Unno
Senior Vice President  General Manager of Corporate Planning Supervisory Div. and General Manager of Corporate Planning Dept.
Yoshio Itaya
Senior Vice President  CFO General Manager of Finance Supervisory Div. and General Manager of Finance & Accounting Dept.
Fumihiko Kamoshida
Senior Vice President  General Manager of Legal Dept.
Toshihiko Komori
Vice President  General Manager of Porfolio Management Unit.
Keiji Kono
Vice President  Deputy Head of Lifecycle Management & Marketing Unit
Shunji Yokoyama
Vice President  Head of Regulatory & Quality Management Unit and General Manager of Drug Safety Div.
Dr. Hisafumi Okabe
Vice President  General Manager of Research Div.
Minoru Machida
Vice President  Deputy General Manager of Pharmaceutical Technology Div. and Chugai Pharma Manufacturing Co., Ltd. (President)
Hitoshi Kuboniwa
Vice President  Department Manager of PT Planning Dept.
Yasushi Ito
Vice President  General Manager of Clinical Development Div.
Tetsuo Minoura
Vice President  Deputy General Manager of Sales Div.
Akio Tanaka
Vice President  Deputy General Manager of Sales Div. (Medical Promotion and Product Research)
Katsuyori Kunii
Vice President  Vice President of Sales Div. (Transplantation Immunology Area Medical Business & Science)
Toshitaka Uto
Vice President  Head of Primary Unit
Susumu Kato
Vice President  Supervisory Branch Manager of Tokyo Branch 1
Mitsuru Kikuchi
Vice President  General Manager of External Affairs Dept.
Mamoru Togashi
Vice President  General Manager of Human Resources Supervisory Div. and General Manager of Human Resources Management Dept.
Kunitoshi Watanabe
Vice President  General Manager of General Affairs Dept.
Toshihiko Tsuchiya
Vice President  General Manager of Secretarial Dept.